8:00am
Registration Opens
Genetics / Proteomics Session
Session Chair: Kenny De Meirleir, M.D.
Session Description: Integrative session: What we have
learned from other illnesses; how gene arrays can help integrate
multidiscipline data; proteomics and its potential as a clinical tool
8:00-8:30am
Introductory Overview
Suzanne D. Vernon, Ph.D.
8:30-9:45am
Genetics / Proteomics Paper Presentations
Genetic Profiles in Severe Forms of Fibromyalgia and Chronic Fatigue Syndrome
Ferran J. García-Fructuoso, M.D.
Genetic contribution to Chronic Fatigue Syndrome (CFS) and associated pain-
and fatigue- related diagnoses described in a population-based genealogical
resource in Utah
Frederick S. Albright, M.S., Ph.D.
KIR Immunogenetics in CFS Italian Patients
Professor Mariaclara Cuccia
Reduced Levels of Oestrogen receptor {beta} mRNA in Swedish Patients
with Chronic Fatigue Syndrome
Birgitta Evengard, M.D., Ph.D.
Proteomic Biosignature of Chronic Fatigue Syndrome in Cerebrospinal Fluid
James Baraniuk M.D.
CFS Heterogeneity Elucidated via Subspace Clustering
Eric R. Aslakson, M.S.
9:45-10:15am
Session Summary: Genetics / Proteomics with a CFS-Perspective
Jonathan R. Kerr, BSc, MBBCh, MD, PhD, FRCPath.
Sir Joseph Hotung Clinical Senior Lecturer in Inflammation
Hon. Consultant in Microbiology, St George’s University of London
10:15-10:30am
Break - Visit Posters & Exhibits
10:30am
Exhibit Hall and Poster Sessions Conclude
New Methods for Evaluating the Fatigue State Session
Session Co-Chairs:
Hirohiko Kuratsune, M.D., D.Med.Sci.
Professor Yasuyoshi Watanabe
Coordinated by the Japanese Association for Fatigue Sciences
10:30-10:50am
BSpectroscopic diagnosis of chronic fatigue syndrome by visible and near-
infrared spectroscopy in serum samples
Akikazu Sakudo, Ph.D.
Research Associate, Department of Virology, Center for Infectious Disease Control,
Research Institute for Microbial Diseases, Osaka University, Department of Physiology,
Osaka City University Graduate School of Medicine, Osaka, Japan
10:50-11:10am
Enhancement of herpes virus 6 (HHV-6) and herpesvirus 7
(HHV-7) reactivation in saliva during the fatigue state
Yoshitaka Kajimoto, M.D.
President and CEO, Soiken, Inc.
Affiliate Professor of Medicine, Wakayama Medical University
11:10-11:30am
Application of DNA chip for Fatigue Assessment
Kazuhito Rokutan, M.D., Ph.D.
Professor & Director, Department of Stress Science,
Institute of Health Biosciences, The University of Tokushima Graduate
School, Tokushima, Japan
11:30-12:30pm
Lunch Break
Viral and Immune Interactions and Health Session
Session Co-Chairs: Dharam V. Ablashi, DVM, MS, Dip. Bact.
Lee Meisel, M.D., J.D.
Session Description: Chronic active viral infection in CFS; diagnostic methodology
issues; sub-grouping by viral status; impact on immune and neurological regulation;
impact of antiviral treatment on outcome.
Coordinated by the HHV-6 Foundation
12:30-1:00pm
Overview of EBV, Stress and Viral Latency in CFS
Ronald Glaser, Ph.D.
Director, Institute for Behavioral Medicine & Professor, Molecular Virology, Immunology & Medical Genetics, Ohio State University, Medical Center.
1:00-1:20pm
Overview of HHV-6 in CFS and Diagnostic Assays for Detecting Chronic Active HHV-6 and EBV
Dharam V. Ablashi, DVM, MS, Dip. Bact.
Co-Founder, Past President and Treasurer, IACFS
Co-Founder, International Epstein-Barr Virus Association
Scientific Director, HHV-6 Foundation
1:20-1:50pm
Immune Paper Presentations
Immunological Comparison of Gulf War Illness and CFS
Mary Ann Fletcher, Ph.D.
Elevated Proinflammatory IL-6 in Patients with Chronic Fatigue Syndrome
Brian M. Gurbaxani, Ph.D.
1:50-3:05pm
Viral Paper Presentations
The HHV6 U45 protein is not a functional dUTPase, but it does induce immune dysregulation similar to the EBV-encoded dUTPase
Marshall V. Williams, Ph.D.
Incidence of HHV-6 and EBV Infection in Chronic Fatigue Syndrome Patients
Susan Levine, M.D.
HHV-6 and HHV-7 Infection in Chronic Fatigue Syndrome
Modra Murovska, Ph.D.
Chronic Fatigue Syndrome is Associated with Persistent Enterovirus Infection of the Stomach
John K. Chia, M.D.
Chronic Bacterial Co-Infections in CFS and CFS Patients Subsequently Diagnosed with Lyme Disease
Garth L. Nicolson, Ph.D.
3:05-3:30 pm
HHV-6 Biology, Viruses and Immunology in CFS
Anthony L. Komaroff, M.D.
Professor of Medicine, Harvard Medical School
3:30-3:45 pm
Closing Remarks
Anthony L. Komaroff, M.D.
Professor of Medicine, Harvard Medical School
3:45pm
General Conference Sessions Concludes
3:45-4:00pm
Break
4:00-5:30pm
Post Conference Workshop: Infections in CFS
Session Description: Non CME bonus session designed
for investigators developing protocols that integrate viral and
immune measures or antiviral or immunomodulatory strategies
Session Co-Chairs: Ronald Glaser, Ph.D.
Dharam V. Ablashi, DVM. MS, Dip Bact
4:00 – 4:45pm Basic Science Panel Discussion
Ronald Glaser, Ph.D.
Dharam V. Ablashi, DVM, MS, Dip. Bact.
John K. Chia, M.D.
Yoshitaka Kajimoto, M.D.
Jonathan R Kerr BSc, MBBCh, MD, PhD, FRCPath.
Constance Knox, Ph.D.
Modra Murovska, Ph.D.
Garth L. Nicolson, M.D.
Marshall Williams, Ph.D.
Session Co-Chairs: Jose G. Montoya, M.D.
Daniel Peterson, M.D.
4:45 - 5:30pm Clinical Science Panel Discussion
Jose G. Montoya, M.D.
Dan Peterson, M.D.
Joe Brewer, M.D.
Nancy Klimas, M.D.
Anthony L. Komaroff, M.D.
Susan Levine, M.D.
Martin Lerner, M.D.