Translating Science into Clinical Care
March 20-23, 2014 • San Francisco, California, USA

Agenda

Thursday, March 20, 2014      

8:00 am - 8:15 am            
Joint Session Welcome & Introduction
Fred Friedberg, Ph.D.
President, IACFS/ME
Research Associate Professor, Stony Brook University

8:15 am - 8:30 am
Joint Session Welcome from Stanford
Jose Montoya, M.D.
Professor of Medicine, Stanford University Medical Center

8:30 am – 9:30 am  (Last 15 Min: Q & A)
Small Game Hunting
Joint Session Special Guest Speaker: Ian Lipkin, M.D.
John Snow Professor of Epidemiology & Director, Center for Infection and Immunity, Columbia University 

Morning Workshop Session: 9:30 am – 12:30 pm

Immunology Primer for Practitioners
Participants of this workshop will receive a brief overview of the immunology of Chronic Fatigue Syndrome including a review of the basic tenants of the innate and acquired immune system with special emphasis on cytotoxic T-cells, natural killer cells, B-cells, and an overview of cytokine formation and function.  Recognized experts in these fields will additionally present the current status of research into the function and dysfunction of these elements of the immune system in CFS/ME and proceed with brief presentations of cutting edge research studies.  Participants by the completion of the discussion session should be able to appropriately order and interpret diagnostic immunological studies on patients presenting with the diagnosis of CFS/ME.  This will facilitate the diagnosis, aid in determining prognosis and enable application of appropriate treatment for subsets of patients.  Finally, a consensus panel will provide a discussion of cost effectiveness, commercial availability, and appropriateness of immunological testing in CFS/ME patients.

Daniel Peterson, M.D., Griffith University, Gold Coast, Australia, Owner, Sierra Internal Medicine, Incline Village, NV
Sonya Marshall - Gradisnik, BSc (Hons), Ph.D. , Professor of Immunology, Director, National Centre for Neuroimmunology & Emerging Diseases, Griffith University, Australia
Sharni Hardcastle, Ph.D., Research Assistant and Practical Demonstrator , Bond University, Gold Coast, Australia
Nancy Klimas, M.D. Ph.D., Professor of Medicine and Director, NSU COM Institute for Neuro-Immune Medicine Director, Miami VAMC Gulf War Illness and ME/CFS Research Program
Paula Waziry, Ph.D, Assistant Professor, Neuro Immune Medicine, COM, Nova Southeastern University, Miami, Fl
Konstance Knox, Ph.D., Founder, CEO, Coppe Healthcare Solutions
David Baewer, M.D. Ph.D, Medical Director, Coppe Healthcare Solutions
Isabel Barao, Ph.D., Research Assistant Professor, University of Nevada, Reno, Simmaron Research Scientific
Gunnar Gottschalk, B.S., Simmaron Research, Incline Village, NV
Troy Querec, Ph.D., Associate Service Fellow, Centers for Disease Control and Prevention, Atlanta, GA
Dennis Mangan, Ph.D., Chair, Trans-NIH ME/CFS Research Working Group, Office of Research on Women's Health, U.S. National Institutes of Health
Mary Ann Fletcher, Ph.D., University of Miami Miller School of Medicine Professor of Medicine, Microbiology/Immunology and Psychology
Elizabeth Unger, M.D. Ph.D., Chief, Chronic Viral Disease Branch, Division of High-Consequence Pathogens and Pathology, National Center for Emerging and Zoonotic Infectious Diseases. Centers for Disease Control and Prevention, Atlanta, GA

Legal Issues and ME/CFS
The workshop will help the participants understand the role of the physician or physician expert in handling requests for information regarding an ERISA or non-ERISA disability claim for one of your patients.  You will learn the basic types of information you will be expected to provide and other types of information it would be useful for you to have to feel confident in supporting your patient’s claim for disability benefits.  Often patient claims are terminated or denied because of a lack of understanding the treating physician has about the process or tricks the insurer or ERISA plan uses.  Further you will learn how to address cold calls from insurers or their doctors or nurses to interview you about one of your patients.  What you say or write can support or torpedo a disability claim.

Steven Krafchick, J.D., MPH
Barbara Arnold, Esq

Exercise Intolerance: Guide to Management and Treatment
Post-exertional malaise (PEM) is a defining characteristic of CFS and a difficult problem to manage for persons with CFS. Our research group has utilized a serial graded exercise test protocol while measuring work output and performing cardiopulmonary analysis to more clearly define PEM. Cardiopulmonary analysis helps to identify cardiac, pulmonary, metabolic and workload-related abnormalities that contribute to PEM. These measurements, made across two days, provide objective documentation for changes in pathology associated with the disease and may be useful for clinical trials examining treatments for this illness. We have proposed the paradigm as a biomarker for PEM in CFS as they appear to relate directly to aerobic system impairment, autonomic dysregulation, and immune dysfunction. This session will also provide a case study based approach to the use of a cardiopulmonary test-retest for identification and quantification of PEM, and provide a conceptual framework for rehabilitation using energy conservation education and analeptic exercise therapy.

Staci Stevens, M.A.
Vice President, IACFS/ME
Christopher Snell, Ph.D.
Professor, University of the Pacific
Mark VanNess, Ph.D.
Associate Professor, University of the Pacific
Todd Davenport, DPT
Associate Professor, University of the Pacific

Translating Science into the Classroom: A Workshop for Clinicians, Patients and Educators
This workshop is intended to facilitate and improve communications between clinicians, educators, and parents when working to support children suffering from ME/CFS in their school environment.  The workshop will include an introduction to the requirements that school administrators, psychologists, educational diagnosticians, and teachers face in providing special services to these students, and how the language chosen by clinicians can be critical in determining whether or not a child will receive special services.  The presentation will explain the “educational jargon” used in public education under IDEA that requires clinicians to justify those services.  Parents and clinicians will be provided with information they can use with schools in situations wherein the existing staff may not have a firm grasp of either ME/CFS or the accommodations that make it possible for children suffering from this illness to succeed.  The presentation will be equally valuable for parents who will learn the "educational jargon" to access services, and become more empowered when discussing their educational needs with the schools and physicians.

Faith Newton, Ed.D.
Associate Professor of Education, Delaware State University

12:30 pm – 1:30 pm
Lunch Break/Visit Exhibits

Afternoon Workshop Session:  1:30 pm – 4:30 pm

Invisible and ignored:  Treating the Severely Ill Patients with CFS/ME and Fibromyalgia (FM)
Up to 25% of persons with CFS/ME or FM may be housebound or bedfast, yet little is written about this severely ill but “invisible” population.   Dr. Lapp will discuss the unique symptoms and complications seen in this group, and offer management strategies.  Dr. Elin Strand and Irma Pinxsterhuis will also discuss their experience managing chronically and severely ill patients from the ME/CFS Unit at Oslo University Hospital, Norway
Charles Lapp, M.D., Medical Director, Hunter-Hopkins Center
Elin Strand, Ph.D., Clinical Psychologist, Oslo University Hospital, ME/CFS Center, Oslo, Norway
Irma Pinxsterhuis, Ph.D. Can., Occupational Therapist, Oslo University Hospital, ME-CFS Unit, Oslo, Norway

Behavioral Assessment and Treatment of ME/CFS and Fibromyalgia (FM)
In this introductory workshop on CFS/ME and fibromyalgia (FM), participants will learn about practical methods of behavioral assessment and individualized treatment strategies. Our approach consists of self-management focused interventions and non-pharmacologic strategies for clinicians that can offer realistic hope for improvement in these patients. This workshop will benefit clinicians who work with CFS/ME and FM patients.
Fred Friedberg, Ph.D. , President, IACFS/ME, Research Associate Professor, Stony Brook University
Leonard A. Jason, Ph.D., Professor, DePaul University

Diagnosing and Treating Orthostatic Intolerance in CFS/ME
This workshop will review the diagnostic criteria, pathophysiology, and overlaps of NMH and POTS, describe the benefits and limitations of standing tests and tilt table tests for the diagnosis of OI in those with CFS/ME, discuss the non-pharmacological treatment of OI, and discuss the more common pharmacological agents used in managing OI syndromes in CFS/ME.
Postural tachycardia and hypotension in response to orthostatic stress are common in those with CFS/ME. These circulatory disturbances contribute to CFS/ME symptoms and lower quality of life. This workshop will help clinicians identify and treat common forms of orthostatic intolerance in their patients with CFS/ME.
Peter Rowe, M.D., Professor of Pediatrics, John Hopkins University School of Medicine

The Management of Pediatric ME/CFS: Translating Research into Clinical Practice
Managing ME/CFS in children and adolescents presents an ongoing challenge to clinicians. This workshop will integrate research and clinical perspectives on the management of pediatric ME/CFS. Particular attention will be paid to effective research translational methods and the practical aspects of ME/CFS management that are unique to the pediatric population.        
Sarah Knight, Research Fellow, Clinical Sciences, Murdoch Children’s Research Institute,
Lionel Lubitz, Associate Professor, University of Melbourne, ³
Kathy Rowe, Pediatrician, Royal Children’s Hospital, Melbourne

5:00 – 5:45 pm 
The Physician-Patient Relationship in the Genomic Era
Joint Session Keynote Speaker:  Abraham Verghese, M.D.
Professor of Medicine, Stanford University Medical School
Best-selling Author, Cutting for Stone

March 21-23, 2014

General Session Agenda-Friday, March 21st

8:30 am – 8:45 am
Welcome and Introduction
Fred Friedberg, Ph.D.
President, IACFS/ME
Research Associate Professor, Stony Brook University
Editor, Fatigue: Biomedicine, Health and Behavior

8:45 am – 9:30 am (last 15 min. are Q and A)   
Plenary Session: How Do We Recognize an Autoimmune Disease?   
Noel R. Rose, M.D., Ph.D.
Director, Center for Autoimmune Disease Research, Johns Hopkins University School of Medicine

Paper Sessions   following short paper presentations each approximately 12 minutes in length, presenters will field questions written on cards by the audience and given to the chair as time permits.

9:30 am – 10:45 am              
Session: The Latest Research in Immunology  
Session Chair: Nancy Klimas, M.D.
Immediate Past President, IACFS/ME
Professor of Medicine & Director, Nova Southeastern University
Director, Miami VAMC Gulf War Illness & ME/CFS Research Program

Allergy-Related Immune Signatures and Duration of Illness in CFS
Susan Levine,1 Xiaoyu Che,2 ,2 W. Ian Lipkin,2 Nancy Klimas,3 Lucinda Bateman,4 Dan Peterson,5 Donna Felsenstein,6 Elizabeth Balbin,7,8 Aundrea Carter,9 Korinne Chu,7 Mary Ann Fletcher,3 Anthony Komaroff,6 Gail Ironson7 and Mady Hornig2

1Private practice, NY, NY; 2Columbia U Mailman School of Public Health, NY, NY; 3Nova Southeastern U, Fort-Lauderdale-Davie, FL; 4Fatigue Clinic, Salt Lake City, UT; 5Simmaron Research Inst, Incline Village, NV; 6Harvard Med School, Boston, MA; 7U of Miami, Miami, FL; 8Miami VA, Miami, FL; 9U of North Carolina, Greensboro, NC; 10Physicians for Peace, Norfolk, VA

Plasma Cytokines in ME/CFS Patients and Controls Before and After a Cardiopulmonary Exercise Test
Ludovic Giloteaux1, Betsy A. Keller2, and Maureen R. Hanson1    
1Cornell University, Dept. of Molecular Biology and Genetics, Ithaca NY, 2Ithaca College, Dept. of Exercise and Sport Sciences, Ithaca NY

Natural Killer Cell Degranulation in Chronic Fatigue Syndrome/Myalgic Encephalomyelitis    
Teilah K. Huth1,2, Ekua W. Brenu1,2, Kirsty Fuller1,2, Sharni L. Hardcastle1,2, Sam Johnston1,2, Donald R. Staines1,3, Sonya M. Marshall-Gradisnik1,2.

1National Centre for Neuroimmunology and Emerging Diseases, Griffith Health Institute, Griffith University, Queensland, Australia.
2School of Medical Science, Griffith University, Southport, Queensland, Australia.
3Gold Coast Public Health Unit, Queensland Health, Queensland, Australia.

Natural Killer Cell Subset Distribution of Lytic Proteins in Chronic Fatigue Syndrome/Myalgic Encephalomyelitis              
Teilah K. Huth1,2, Ekua W. Brenu1,2, Sharni L. Hardcastle1,2, Kirsty Fuller1,2, Sam Johnston1,2, Donald R. Staines1,3, Sonya M. Marshall-Gradisnik1,2.

1National Centre for Neuroimmunology and Emerging Diseases, Griffith Health Institute, Griffith University, Queensland, Australia.
2School of Medical Science, Griffith University, Southport, Queensland, Australia.
3Gold Coast Public Health Unit, Queensland Health, Queensland, Australia.

A Genome-wide Analysis of Differential Methylation Associated with Chronic Fatigue Syndrome
Mangalathu S. Rajeevan†, Virginia Falkenberg, Irina Dimulescu, Elizabeth R. Unger
Centers for Disease Control and Prevention, Atlanta, GA

10:45 am – 11:15 am
Break / Visit Exhibits

11:15 am12:15 am
Session: Virology Research    
Chair:  Jose Montoya, M.D.
Professor of Medicine, Stanford University Medical Center

Chronic Pelvic Pain (CPP) in Patients with Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) is Associated with Chronic Enterovirus Infection of Ovarian Tubes
John Chia, M.D., David Wang, Rabiha El-habbal and Andrew Chia, EV Med Research, Lomita California

Occurrence of Typical Clinical Symptoms and Markers of Human Parvovirus B19 Infection in Patients with Myalgic Encephalomyelitis/Chronic Fatigue Syndrome
Santa Rasa1, Svetlana Chapenko1, Angelika Krumina2, Ludmila Viksna2, Modra Murovska1
1August Kirchenstein Institute of Microbiology and Virology, Riga Stradinš University, Latvia
2Department of Infectology and Dermatology, Riga Stradinš University, Latvia

Pathogenesis of chronic enterovirus infection in myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) –in vitro and in vivo studies of infected stomach tissues
John Chia, M.D., Andrew Chia, David Wang, Rabiha El-Habbal. EV Med Research. Lomita, CA

12:15 pm– 1:45 pm
Lunch Break/Visit Exhibitors

12:15 pm - 1:15 pm
The Chronic Fatigue Initiative (CFI)- Findings from the CFI Cohort Study and Pathogen Discovery & Pathogenesis Project
Open to all attendees and includes a complimentary lunch
Scott Carlson, Mady Hornig, M.D., Ph.D., Nancy Klimas, M.D., and Gail Ironson, M.D, Ph.D., Dana March, Ph.D.  and Anthony Komaroff, M.D.
Non-CME symposium sponsored by the Chronic Fatigue Initiative

1:45 pm – 3:00 pm               
Session: Treatment Studies     
Chair: Daniel Peterson, M.D.

Treatment of Orthostatic Intolerance (OI) Using Midodrine in Patients with Chronic Fatigue Syndrome (CFS); and Assessment Using Hours of Vertical Activity (HVA)
Nicole Baldwin
St. Olaf College, Northfield, MN, and *Lucinda Bateman MD, Fatigue Consultation Clinic, Salt Lake City, UT. 

Intervention Effect of Baduanjin Exercise on the Fatigue State in People with Fatigue-predominant Sub-health – A Cohort Study
Wang Tian-fang1  Liao Yan1, Zhang Cong1, Zhang Yu1, Xue Xiao-lin1, Dai Jin-gang2, Lin Yin1
1 School of Preclinical Medicine, Beijing University of Chinese Medicine, Beijing 100029; 2 China Academy of Chinese Medical Sciences)

Effect of Isometric Yoga on Chronic Fatigue Syndrome: A Randomized Controlled Trial
Takakazu Oka, Tokunari Tanahashi, Takeharu Chijiwa, Nobuyuki Sudo
Graduate School of Medical Sciences, Kyushu University

Home-Based Self-Management for Severe CFS/ME:  A Randomized Trial
Fred Friedberg, Ph.D.

3:00 pm – 3:30 pm                
Break / Visit Exhibits

3:30 pm – 5:30 pm    
Session: Diagnosing CFS/ME; Difficult Clinical Cases
Session Chair: Nancy Klimas, M.D.
Immediate Past President, IACFS/ME
Charles Lapp, M.D.
Lucinda Bateman, M.D.
Rosamund Vallings, MNZM, MB BS
Daniel Peterson, M.D.

5:30 pm – 6:15 pm   
Visit Poster Presentations / Exhibits

6:00 pm – 7:00 pm
K-PAX Pharmaceuticals Social/Cocktail Hour
The Synergy Trial Update
Non CME Function Open to All Attendees
Mission Room - 4th Floor

General Session Agenda-Saturday, March 22nd   

8:30 am – 10:00 am              
Session: Case Definitions for Research and Practice    
Chair: Kenneth Friedman, Ph.D.
Treasurer, IACFS/ME
Adjunct Instructor, Castleton State College

A Comparison of the Case Definitions
Leonard Jason, Ph.D.
Professor, DePaul University, Director of the Center for Community Research

Physical and social functioning in varying cases of Chronic Fatigue Syndrome/Myalgic Encephalomyelitis & Immune and physical status in patients meeting new criteria for Chronic Fatigue Syndrome/Myalgic Encephalomyelitis
Johnston S.1, Brenu E.W.1, Hardcastle S1, Huth T.K.1, Fuller K1, Ramos S.B.1, Staines D.R.1,2, Marshall-Gradisnik, S.1.

1
Griffith Health Institute, School of Medical Sciences, National Centre for Neuroimmunology and Emerging Diseases, Griffith University, Gold Coast, Australia
2 Gold Coast Public Health Unit, Queensland Health, Gold Coast, Australia

Immune and physical status in patients meeting new criteria for Chronic Fatigue Syndrome/Myalgic Encephalomyelitis
Johnston S.1, Brenu E.W.1, Hardcastle S1, Huth T.K.1, Fuller K1, Ramos S.B.1, Staines D.R.1,2, Marshall-Gradisnik, S.1.
1 Griffith Health Institute, School of Medical Sciences, National Centre for Neuroimmunology and Emerging Diseases, Griffith University, Parklands, QLD, Australia
2 Gold Coast Public Health Unit, Queensland Health, Robina, QLD, Australia

Case Definitions: Diagnostic and Criterion Issues
Leonard A. Jason (Ph.D., DePaul University), Madison Sunnquist (B.S., DePaul University)

10:00 – 10:30 am
Break/Visit Exhibits


10:30 am – 12:00 pm            
Part I Session Public Health Research     
Chair: Lily Chu, M.D.

CFS/ME and Fatiguing Illnesses: Differential Diagnoses from a Community-Based Sample
Nicoletta Carlo-Stella MD, PhD, free professional, Pavia, Italy

Expanding Access to Knowledgeable Healthcare for Neuro-endocrine-immune Diseases in Alabama – A Case Study
Tina M. Tidmore1, Lori Chapo-Kroger, RN2
1Tidmore Communications, 2PANDORA Org

Family Aggregation Studies in CFS
Alegre J, Castro-Marrero J, Ribases M, Aliste L, Saez N, Calvo N, Marquino A, Fernandez de Sevilla T and Fibromyalgia and CFS Spanish Genetic and Clinical Data Bank (FSGCDB Group) and Foundation FF.
Chronic Fatigue Group. Vall d´Hebron University Hospital Research Institute. Universidad Autònoma de Barcelona. Barcelona. Spain

The UK ME/CFS Biobank: 2 Years of Experience 
Eliana M Lacerda, Erinna W Bowman, Sunita Nagpal, Ronnie Chee, Luis C Nacul

The Lay-Scientific Partnership That Shaped and Development of the UK ME/CFS Biobank
Eliana M Lacerda, Erinna W Bowman, Luis C Nacul

12:00 pm – 1:15 pm
Lunch Break/Visit Exhibits

12:00 pm – 1:00 pm
Special Interest Meeting – Medical Education for CFS/ME
Susan Levine, M.D.
Non CME Function Open to All Attendees - participants are encourage to bring a lunch and attend Mission Room #2- 4th Floor

12:00 pm – 1:00 pm
Special Interest Meeting – Cardiopulmonary Exercise Testing and Disability Evaluation
Christopher Snell, Ph.D.
Non CME Function Open to All Attendees – participants are encourage to bring a lunch and attend Mission Room #3- 4th Floor

12:00 pm – 1:00 pm
Special Interest Meeting – Communicating CFS/ME: Can You Hear Me?
Dennis Mangan, Ph.D.
Non CME Function Open to All Attendees - participants are encourage to bring a lunch and attend Mission Room #1- 4th Floor

1:15 pm – 2:30 pm
Part II Session Public Health Research     
Chair: Elizabeth Unger, M.D., Ph.D.
Chief, Chronic Viral Diseases Branch, Division of High-Consequence Pathogens and Pathology National Center for Emerging and Zoonotic Diseases, Centers for Disease Control and Prevention

Prevalence and Health-related Characteristics of Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS), Fibromyalgia (FM) and Environmental Sensitivities/Multiple Chemical Sensitivity (ES/MCS): Results from the Canadian Community Health Survey (CCHS) 2005, 2010 and 2012
M. Parlor, National ME/FM Action Network, Halapy E, Ontario Centre of Excellence in Environmental Health Business Case Project

The Natural Course of Chronic Fatigue Syndrome: Evidence from a Multi-Site Clinical Epidemiology Study
Dana March, Ph.D., Assistant Professor, Department of Epidemiology, Columbia University Mailman School of Public Health

What Treatments Alter the Course of Chronic Fatigue Syndrome? Evidence from a Multi-Site Clinical Epidemiology Study
Lucinda Bateman, M.D., Adjunct Assistant Professor, Department of Anesthesiology, University of Utah

Chronic Fatigue Syndrome and Comorbid and Consequent Conditions: Evidence from a Multi-Site Clinical Epidemiology Study
Salima Darakjy, MPH, Ph.D. Candidate, Department of Epidemiology, Columbia University

2:30 pm – 2:45 pm                 
Break / Visit Exhibits

2:45 am – 4:15 pm               
Session: Provocation Studies     
Chair: Staci Stevens, M.A.
Vice President, IACFS/ME
Work Well Foundation, Founder

Superior Ability of a Two-Day CPET Protocol to Detect Functional Impairment in ME/CFS Compared to Either a Single CPET, A Submaximal Exercise Test, or a VO2 Prediction Equation
Betsy A. Keller,   Ithaca College, Dept. of Exercise and Sport Sciences, Ithaca NY

Diminished Pulmonary Ventilation in CFS Patients – Effects of Deconditioning and Post-Exertional Malaise
J. Mark VanNess, Ph.D.
Associate Professor, University of the Pacific

Submaximal Exercise Testing Using Near Infrared Spectroscopy (NIRS) May Not Differentiate Those With Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) From Healthy Controls
Miller, RR1; Reid, WD2; Mattman, A1; Yamabayashi, C2; Steiner, T1; Parker, S3; Tang, P1; Gardy, JL1; Patrick, DM1 for the Chronic Complex Disease (CCD) Study Team

1University of British Columbia 2Dept of Physical Therapy; RAMP Lab, Vancouver Coastal Health Research Institute 3Centre for Health Evaluation and Outcome Sciences, Providence Health Care

Oxygen Extraction and Lactate Are Low during Cardiopulmonary Exercise Test in Patients with Chronic Fatigue Syndrome
RCW Vermeulen, WG Vermeulen – van Eck and I.V. de Jong – Medvetska
Head of Research, CVS Centrum Amsterdam,

Specific Fitness Profile to Effort in CFS
Alegre J1, Suarez A2, García-Quintana AM2, Castro-Marrero J1, García-Quintana J2.
1Chronic Fatigue Group. Vall d´Hebron University Hospital Research Institute. Universidad Autónoma de Barcelona. Spain. 2CFS Unit. Centro Médico Delfos. Barcelona. Spain                                                  

4:15 pm – 5:15 pm
Visit Poster Presentations / Exhibits

5:15 pm – 6:00 pm
IACFS/ME Membership Business Meeting

6:00 pm – 7:00 pm
IACFS/ME Social/Cocktails Hour

7:00 pm – 8:00 pm
IACFS/ME Banquet Dinner

8:00 pm – 9:00 pm               
Awards Presentation & Banquet Keynote
Daniel L. Peterson, M.D.
"CFS/ME and the IACFS/ME: Past, Present and Future"

General Session Agenda-Sunday, March 23rd   

8:00 am – 9:15 am
Part I Session: Advances in Pediatric ME/CFS Research      
Chair: Leonard A. Jason, Ph.D.
Professor, DePaul University, Director of the Center for Community Research

How is Pediatric Chronic Fatigue Syndrome/Myalgic Encephalomyelitis (CFS/ME) diagnosed and managed by Pediatricians? An Australian National Study
Sarah Knight1,2,3,4, Adrienne Harvey1,2,3,5, Susan Towns6, Donald Payne7,8, Lionel Lubitz9, Kathy Rowe9,10, Colette Reveley9,10, Frederika Veit10, Sabine Hennel2, Mike South1,3,9 and Adam Scheinberg1,2,5,11

Impaired Range of Motion in Adolescent Chronic Fatigue Syndrome
Peter C. Rowe, M.D.1, Colleen L. Marden1, Marissa A. K. Flaherty1, Samantha E. Jasion1, Erica M. Cranston1, Allison S. Johns1, John Fan1, Kevin R. Fontaine, Ph.D.2, Richard L. Violand, PT.3

From the 1Department of Pediatrics, Johns Hopkins University School of Medicine, Baltimore, MD, the 2Department of Health Behavior, University of Alabama at Birmingham School of Public Health, Birmingham, AL, and 3Violand and McNerney, PA, Ellicott City, MD, USA

Tracking Post-infectious Fatigue in Clinic using Routine Clinical Lab Tests
Alanna Bowie1, Jeanna M Harvey2,6, Ben Z. Katz 3, Frederick A. Smith 4, Maurice R.G. O’Gorman 3,4, R. Taylor 5, Mary Ann Fletcher 6, Nancy G Klimas 6, Gordon Broderick 6

1 Department of Medicine, University of Alberta, Edmonton, AB, Canada, 2 Department of Medicine, University of Miami, Miami, FL, 3 Div. Infectious Diseases, Children’s Memorial Hospital, Chicago, IL, 4 Dept. of Pathology, Feinberg School of Medicine, Northwestern, Chicago, IL, 5 Dept. of Occupational Therapy, University of Illinois at Chicago, Chicago, IL, 6 Institute for Neuro-Immune Medicine, Nova Southeastern University, Fort Lauderdale, FL

Increased Prevalence of Delayed Milk Protein Hypersensitivity Among Adolescents and young Adults with Chronic Fatigue Syndrome
Peter C. Rowe, M.D.1, Colleen L. Marden1, Samantha E. Jasion1, Erica M. Cranston1, Marissa A. K. Flaherty1, Kevin J Kelly, M.D 2

From the 1Department of Pediatrics, Johns Hopkins University School of Medicine, Baltimore, MD 2 Pediatric Specialty Care, Willow Grove, PA, USA

9:15 am – 10:30 am               
Part II Session: Advances in Pediatric ME/CFS Research   
Chair: Rosamund Vallings, M.B., M.S.

Impact of Adolescent Chronic Fatigue Syndrome
Peter C. Rowe, M.D.1, Colleen L. Marden1, Marissa Flaherty1, Allison S. Johns1,
John Fan1, Kevin R. Fontaine, PhD,2 Rick L. Violand, PT3.

From the 1Department of Pediatrics, Johns Hopkins University School of Medicine, Baltimore, MD, 2Department of Health Behavior, University of Alabama at Birmingham School of Public Health, Birmingham, AL, and 3Violand and McNerney, Ellicott City, MD, USA

What Do Young People Find Helpful in Managing Their Chronic Illness? Lessons From Chronic Fatigue Syndrome
Katherine Rowe, MJBBS, MD, FRACP Royal Children’s Hospital, Murdoch Children’s Research Institute, Melbourne, Australia

Sleep Education During Elementary School Prevents School Non-Attendance in Junior High School Years
Seiki Tajima1, Teruhisa Miike1, Tsutomu Maeda2.

1Hyogo children’s sleep and development medical research center, Hyogo, Japan.
2Nonprofit organization RIFOUMU WAKASA, Fukui, Japan.

Does Depression at Presentation Impact on Outcomes for Young People With CFS?
Katherine Rowe, MJBBS, M.D., FRACP Royal Children’s Hospital, Murdoch Children’s Research Institute, Melbourne, Australia

10:30 am – 10:45 pm           
Break

10:45 am – 12:00 pm
Session:  Advances in Brain Research    
Simcox-Clifford-Higby Professor of Medicine, Harvard Medical School

Neuroscience of Fatigue and CFS/ME by Using PET Molecular Imaging and Functional Neuroimaging
Yasuyoshi Watanabe1,2, Masaski Tanaka1,2, Kei Mizuno1,2, Akira Ishii1,2, Emi Yamano1,2, Sanae Fukuda1-3, Yasuhito Nakatomi1-3, Kouzi Yamaguti3,4, and Hirohiko Kuratsune2-4

1RIKEN Center for Life Science Technologies, Kobe, Japan, 2Department of Physiology, 3Fatigue Clinical Center, Osaka City University Graduate School of Medicine, 4Department of Health Science, Kansai University of Welfare Sciences, Osaka, Japan.

EEG Peak Alpha Frequency is Associated with Chronic Fatigue Syndrome: A Case-Control Observational Study 
Marcie Zinn, Ph.D., Mark Zinn, MM, Jose Maldonado, MD, FAPM, Jane Norris, PA-C, Ian Valencia, BS

Cortical Hypoactivation During Resting EEG suggests Subcortical Pathophysiology in Chronic Fatigue Syndrome as Revealed by Exact Low Resolution Electromagnetic Tomography
Mark A Zinn , Marcie L Zinn1, Jose R Maldonado2, Jane L Norris1, Ian Valencia1, Jose G Montoya1,3 

1Department of Infectious Diseases and Geographic Medicine, Stanford University Medical Center, Palo Alto, CA, USA 2Department of Psychiatry and Behavioral Sciences, Stanford School of Medicine, Stanford, CA, USA  3Stanford University School of Medicine, Stanford, CA, USA 

Cognitive Functioning in Chronic Fatigue Syndrome
Susan J. Cockshell, Jane L. Mathias, The University of Adelaide, Australia

12:00 pm – 1:15 pm             
Lunch / Visit Exhibits
Networking Lunch – Offering an opportunity for clinicians to network and talk about assessment and treatment issues.

1:15 pm – 2:15 pm  
Session: IACFS/ME Clinical Practice Manual: The 2014 Revised Primer
Guidelines Panel Chair: Fred Friedberg, Ph.D.
Panel: Lucinda Bateman, M.D., Kenneth Friedman, Ph.D., Leonard Jason, Ph.D., Charles Lapp, M.D., Lucinda Bateman, M.D., Staci Stevens, M.A.,  Rosamund Vallings, M.B., B.S.

2:15 pm – 2:45 pm               
Summary of the Conference
Anthony L. Komaroff, M.D.

2:45 pm                                  
Conference Concludes